Table 3 Changes in cardiac structure and function from baseline to 12 months in randomized controlled trials.

From: Effects of Renal Denervation on Cardiac Structural and Functional Abnormalities in Patients with Resistant Hypertension or Diastolic Dysfunction

  

LVMI

E/e’

BNP (ng/L)

EF

LVDD (mm)

LAVI (ml/m2)

Rosa et al.

Change from baseline in RDN

−1.6 ± 14.4 (g/m2.7)

−0.1 ± 6.6

NR

0.01 ± 0.07

−0.6 ± 4.3

−0.3 ± 20.1

Change from baseline in PT

−4.0 ± 11.1(g/m2.7)

−0.8 ± 5.1

NR

0.02 ± 0.11

−1.4 ± 5.6

1.0 ± 17.6

Difference in change (P value)

P = 0.36

P = 0.58

NR

P = 0.61

P = 0.42

P = 0.71

Patel et al.

Change from baseline in RDN

0.7 ± 4.3 (g/m2)

0.2 ± 4.4

−3 (−59, 33)

NR

NR

6.5 ± 13.2

Change from baseline in PT

0.2 ± 3.2 (g/m2)

0.2 ± 1.2

18 (−2, 30)

NR

NR

2.4 ± 8.9

Difference in change (P value)

P = 0.807

P = 0.962

P = 0.559

NR

NR

P = 0.504

  1. Data are presented as mean ± standard deviation or median (quartile 1, quartile 3). LVMI: left ventricular mass; E/e’: ratio of mitral inflow velocity to annular relaxation velocity; LLVDD: left ventricular diameter in diastolic; BNP: B-type natriuretic peptide; EF: ejection fraction; LAVI: left atrial volume index. Other abbreviations as in Table 1.
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