Figure 4
From: Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V
Exportin-1/Ran-GTP and importin α2/β1 induce folding of wild-type HeV V and V variants. CD spectra of (a,b) V, (c,d) VL174A/L177A, (e,f) V1-405, and (g,h) V51-457 are shown in black, with the spectra of (a,c,e,g) exportin-1/Ran-GTP and (b,d,f,h) importin α2/β1 in blue and green, respectively. Spectra of equimolar mixtures (obs) of V:importin α2/β1 (orange) and V:exportin-1/Ran-GTP (magenta) are shown. Theoretical average curves (calc) calculated by assuming that no structural variations occur (see Methods) are shown in gray.
