Figure 3 | Scientific Reports

Figure 3

From: Transcriptome profile of NO-induced Arabidopsis transcription factor genes suggests their putative regulatory role in multiple biological processes

Figure 3

An average of 30% TFs were involved in defence. Functional classification of TFs involved in different cellular process and defence. Out of all NO-induced TFs, 193 were involved in defence and 31 in development. The red-blue colour key indicates up- and down-regulated genes, respectively. The bottom-right section of the figure represents ubiquitin proteasome system (UPS) that acts in ATP-dependent manner with Regulatory Particle Triple-A ATPase 3 (RPT3). Proteins are targeted to the proteasome by tagging with small ubiquitin protein (red balls) through a 3 step processes. First E1 ubiquitin-activating enzyme is covalently linked with an ubiquitin protein which is then transferred to a E2 ubiquitin-conjugating enzyme. This activates the E3 ubiquitin ligase complex having RING U-box and HECT (homologous to E6-assoicated protein C terminus) domain proteins that mediates transfer of ubiquitin to lysine residue in the substrate thus marking them for proteasomal degradation. About 7 different NO-responsive TFs were mapped to the E3 ubiquitin-ligase complex suggesting NO role in UPS.

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