Figure 2
From: Human mesenchymal stem cells lose their functional properties after paclitaxel treatment
Paclitaxel does not affect the defining surface marker expression, but impairs the adhesion and migration capabilities of MSCs. (a) Representative flow cytometry analyses of defining positive MSC markers CD73, CD90 and CD105 and negative markers CD14, CD20, CD34 and CD45 at 24 and 48 hours after treatment with 15 nM paclitaxel. (b) Relative adhesion rates of MSCs and differentiated fibroblasts up to 24 hours after treatment with paclitaxel (n = 5). (c) Average velocity of MSCs and differentiated fibroblasts after paclitaxel treatment. Data are mean +/− SD. n.s.: not significant; *P < 0.05; **P < 0.01.
