Figure 5

R-parameter captures significant difference between ASD and mature TD. (A) Location of each subject in the ASD group (29 subjects) and the mature TD group (15 subjects) on the R-space (x-axis is the R-parameter value). The space was colored used the logistic regression result \(H(R)=g(0.30R-20.89)\), g is sigmoid function). (B) Distribution of R-parameter values among each group. The separation of the two groups is significant, with t-test ‘p’ value close to zero (below 10⁻¹¹). (C) Shows a remarkable age-related maturation transition in typical development: here we compare R-parameter value results for 6 young TD children (3–5 years old) to 15 mature TD adults (19–31 years old). (D) Shows R-parameter results vs subject ages in the ASD group: notice the absence of an age correlated transition, concentrating all the R values to the lower ASD region. 26 subjects were included in the plot, the other 3 subjects’ ages (above 14 yrs) were missing in the records. The correlation coefficient between R and age in this group is −0.17, with p value equals 0.40.