Figure 7

Filial ASD link and further R-parameter robustness validation (A) R-parameter results from measurements in 20 parents of 13 ASD subjects in our cohort compared to typical control adults. Most parents (17 out of 20, with 10 mothers and 7 fathers) fell within the ASD region on the R-space. They are clearly separated from typical control individuals. (B) Parent’s age vs. R-values: no correlation is found. Having correlation coefficient 0.15 and p value 0.53. (C) TD control variation R-parameter test when varying the experimental conditions: (1) by changing the trajectory (adding restriction to the motion trajectory) (test on 7 subjects); (2) by changing target sizes (from 5 cm to 1 cm) (test on 15 subjects); (3) left-hand testing (all subjects were right handed) (test on 12 subjects). Data points were labeled by their R-value rank against the default condition. Notice the consistence of the R values under various conditions. All subjects remain in or near to the TD region in R-space, as in the default condition, suggesting the robustness of our R-results. The R biomarker value captures individual’s motion features that are independent of task design.