Figure 4 | Scientific Reports

Figure 4

From: Discovery of Hepatotoxic Equivalent Combinatorial Markers from Dioscorea bulbifera tuber by Fingerprint-Toxicity Relationship Modeling

Figure 4

(A) Content of EEA and DIOB and the serum ALT and AST activities of 21 batches of DBT extracts (S01–S21, 2 g/kg). (B) The heat map of the combination of DIOB and EEA contents and the serum ALT/AST levels, the shade of colors meant different concentration levels of the combination of these two compounds and ALT/AST. The orange or bluer the color were the higher or lower the relative concentration level. (C) Histological observation of DBT extracts induced liver injury. Control (a); b, c, d, e and f were representative images show H&E staining of liver tissue from experimental groups. (Original magnification: ×200).

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