Table 4 Baseline clinical parameters of the investigated study cohort.

From: Human complement receptor type 1 (CR1) protein levels and genetic variants in chronic Chagas Disease

 

Indeterminate (n = 92)

Cardiac (n = 87)

Digestive (n = 21)

Cardiodigestive (n = 32)

Controls (n = 104)

Age [Range]

57 [34–76]

51 [34–90]

57 [36–81]

57 [37–73]

51 [37–72]

Sex (Male/Female)

34/58

46/41

15/16

18/14

54/50

Ethnicity (Euro-Brazilian/Others)

80/12

58/29

15/6

23/9

91/13

Cardiac impairment (A,B,C,D)*

NA

(27,22,36,02)

NA

(11,07,12,02)

NA

Erythrocytes (RBCs) (Million cells/µL), [Range]

4.7 [4.2–6.5]

5.0 [3.6–6.0]

4.8 [4.2–6.5]

5.0 [4.3–5.6]

NA

Hemoglobin (mg/dL), [Range]

14.4 [10.9–45.7]

14.8 [9.0–17.7]

14.6 [13.2–17.3]

14.9 [12.9–17.4]

NA

uCRP levels (mg/dL), [Range]

0.33 [0.08–3.77]

0.34 [0.08–4.25]

0.19 [0.09–0.38]

0.34 [0.08–0.76]

NA

CR1 levels (ng/mL), [Range]

11.73 [6.16–51.61]

10.72 [6.16–37.93]

9.46 [6.74–53.17]

9.64 [7.34–40.97]

17.25 [6.69–67.35]

LVEF (%), [Range]

70 [35–84]

65 [45–82]

NA

66 [47–77]

NA

  1. NA: Not applicable.
  2. *Cardiac patients were graded according to the cardiac insufficiency classification of the American Heart Association (AHA) adapted for CD.
  3. RBCs: Red blood cells.
  4. uCRP: Ultrasensitive C-reactive protein.
  5. CR1: Complement receptor 1.
  6. LVEF: Left ventricular ejection fraction.