Table 1 MicroRNAs differentially expressed between tumor and healthy adjacent tissue in patients diagnosed with HNSCC.
From: Tissue and serum microRNA profile of oral squamous cell carcinoma patients
miRNA | Healthy1 | Tumor1 | FC2 | P Value | FDR3 |
|---|---|---|---|---|---|
Down-regulated | |||||
hsa-miR-204-5p | 344.22 ± 91.11 | 17.55 ± 4 | 0.06 | 3.51E-07 | 1.28E-05 |
hsa-miR-375 | 8,515.05 ± 3731.04 | 1,026.33 ± 475.78 | 0.09 | 1.18E-08 | 1.50E-06 |
hsa-miR-4497 | 163.05 ± 43.63 | 38.93 ± 25.6 | 0.11 | 1.51E-05 | 0.0003 |
hsa-miR-1291 | 25.55 ± 6.65 | 4.97 ± 2.86 | 0.12 | 0.0006 | 0.0048 |
hsa-miR-4492 | 2,079.89 ± 449.49 | 623.76 ± 345.65 | 0.14 | 0.0004 | 0.0034 |
hsa-miR-3196 | 52.91 ± 11.59 | 15.47 ± 8.59 | 0.14 | 0.0015 | 0.0098 |
hsa-miR-6087 | 863.11 ± 228.33 | 197.8 ± 98.4 | 0.14 | 3.84E-05 | 0.0005 |
hsa-miR-4508 | 513.24 ± 82.05 | 165.24 ± 87.58 | 0.15 | 1.26E-04 | 0.0015 |
hsa-miR-4485-3p | 1,123.14 ± 122.84 | 342.32 ± 174.79 | 0.16 | 5.28E-05 | 0.0006 |
hsa-miR-3195 | 169.22 ± 26.06 | 56.78 ± 31.03 | 0.16 | 0.0004 | 0.0034 |
hsa-miR-3687 | 132.19 ± 33.34 | 43.88 ± 27.87 | 0.17 | 0.0009 | 0.0067 |
hsa-miR-3648 | 43.98 ± 11.65 | 12.65 ± 6.93 | 0.17 | 0.0011 | 0.0079 |
hsa-miR-6510-3p | 163.94 ± 74.97 | 20.35 ± 4.35 | 0.17 | 0.0007 | 0.0054 |
hsa-miR-4516 | 1635 ± 411.42 | 504.11 ± 268.88 | 0.17 | 0.0006 | 0.0048 |
hsa-miR-7704 | 660.64 ± 175.7 | 219.49 ± 129.52 | 0.18 | 0.0003 | 0.0033 |
hsa-miR-3656 | 622.23 ± 139.7 | 202.24 ± 92.26 | 0.21 | 0.0020 | 0.0122 |
hsa-let-7c-5p | 4,812.94 ± 1102.21 | 1,129.95 ± 257.38 | 0.23 | 1.38E-07 | 1.17E-05 |
hsa-miR-4532 | 5,351.31 ± 955.34 | 1,714.59 ± 702 | 0.23 | 3.93E-05 | 0.0005 |
hsa-miR-4488 | 489.12 ± 102.88 | 187.6 ± 85.58 | 0.25 | 0.0056 | 0.0305 |
hsa-miR-99a-3p | 20.09 ± 2.83 | 5.35 ± 1.5 | 0.25 | 0.0053 | 0.0296 |
hsa-miR-125b-5p | 2,016.76 ± 257.48 | 619.77 ± 211.97 | 0.26 | 3.57E-05 | 0.0005 |
hsa-miR-139-5p | 77.3 ± 10.43 | 21.21 ± 4.97 | 0.26 | 1.89E-05 | 0.0003 |
hsa-miR-3651 | 37.03 ± 7.24 | 12.6 ± 5.58 | 0.26 | 0.0068 | 0.0362 |
hsa-miR-125b-2-3p | 632.01 ± 120.54 | 169.59 ± 28.9 | 0.27 | 3.77E-06 | 8.73E-05 |
hsa-miR-99a-5p | 1,185.4 ± 41.23 | 395.01 ± 93.85 | 0.30 | 3.26E-05 | 0.0005 |
Up-regulated | |||||
hsa-miR-31-3p | 1.16 ± 0.98 | 39.8 ± 7.41 | 77.11 | 2.91E-06 | 8.73E-05 |
hsa-miR-424-5p | 2.14 ± 1.86 | 39.75 ± 7.37 | 71.59 | 9.64E-06 | 2.05E-04 |
hsa-miR-196b-5p | 2.02 ± 1.75 | 30.15 ± 10.01 | 45.71 | 3.89E-05 | 0.0005 |
hsa-miR-877-5p | 1.27 ± 1.09 | 18.72 ± 5.12 | 35.80 | 0.0003 | 0.0031 |
hsa-miR-7-5p | 1.72 ± 1.56 | 12.84 ± 3.27 | 19.87 | 0.0004 | 0.0034 |
hsa-miR-135b-5p | 4.14 ± 2.98 | 44.97 ± 7.22 | 17.78 | 2.62E-07 | 1.20E-05 |
hsa-miR-31-5p | 128.27 ± 21.82 | 2,528.87 ± 1130.27 | 14.86 | 1.24E-10 | 3.17E-08 |
hsa-miR-142-3p | 12.2 ± 6.43 | 94.3 ± 26.39 | 11.70 | 2.82E-07 | 1.20E-05 |
hsa-miR-187-3p | 3.52 ± 1.93 | 25.4 ± 6.59 | 8.44 | 0.0003 | 0.0031 |
hsa-miR-19a-3p | 6.74 ± 3.3 | 33.87 ± 10.76 | 7.43 | 0.0018 | 0.0114 |
hsa-miR-708-3p | 4.06 ± 1.25 | 25.92 ± 3.89 | 6.34 | 3.45E-06 | 8.73E-05 |
hsa-miR-223-3p | 63.71 ± 13.03 | 442.93 ± 139.65 | 6.16 | 2.24E-07 | 1.20E-05 |
hsa-miR-32-5p | 5.49 ± 2.43 | 24.26 ± 6.04 | 4.91 | 0.0006 | 0.0046 |
hsa-miR-18a-5p | 24.29 ± 5.7 | 123.25 ± 36.61 | 4.84 | 3.66E-06 | 8.73E-05 |
hsa-miR-301a-3p | 9.17 ± 2.54 | 46.43 ± 12.17 | 4.52 | 0.0002 | 0.0021 |
hsa-let-7a-3p | 23.56 ± 16.17 | 52.02 ± 10.75 | 4.32 | 0.0027 | 0.0164 |
hsa-miR-21-5p | 11,577 ± 2360.39 | 40,506.05 ± 5524.39 | 3.56 | 2.58E-05 | 0.0004 |
hsa-miR-455-5p | 18.77 ± 2.14 | 61.45 ± 8.19 | 3.12 | 0.0004 | 0.0034 |
hsa-miR-92b-3p | 497.22 ± 94.34 | 1465.13 ± 210.46 | 3.02 | 0.0004 | 0.0034 |
hsa-miR-21-3p | 1,366.33 ± 343.19 | 3,663.11 ± 527.37 | 2.90 | 0.0016 | 0.0107 |
hsa-miR-142-5p | 816.58 ± 219.92 | 2,412.08 ± 695.48 | 2.64 | 0.0043 | 0.0254 |
hsa-miR-944 | 58.54 ± 12.98 | 146.36 ± 19.26 | 2.56 | 0.0053 | 0.0296 |
hsa-miR-20a-5p | 87.07 ± 12.5 | 214.73 ± 26.33 | 2.41 | 0.0044 | 0.0257 |
