Table 2 Top 20 pathways of target genes from the 48 miRNAs differentially expressed between tumor and healthy tissue of HNSCC patients.
From: Tissue and serum microRNA profile of oral squamous cell carcinoma patients
KEGG pathway | P value1 | Genes2 | miRNAs3 |
|---|---|---|---|
Hippo signaling pathway | 8.98E-09 | 102 | 33 |
Signaling pathways regulating pluripotency of stem cells | 2.18E-08 | 96 | 34 |
Fatty acid biosynthesis | 8.41E-07 | 7 | 18 |
Axon guidance | 1.16E-06 | 84 | 31 |
Proteoglycans in cancer | 2.08E-06 | 126 | 34 |
Pathways in cancer | 8.41E-06 | 234 | 41 |
TGF-beta signaling pathway | 8.56E-06 | 52 | 30 |
Endocytosis | 8.56E-06 | 129 | 38 |
Glutamatergic synapse | 9.06E-06 | 72 | 33 |
Glioma | 1.11E-05 | 45 | 31 |
Neurotrophin signaling pathway | 1.11E-05 | 84 | 33 |
Pancreatic cancer | 1.46E-05 | 48 | 27 |
Wnt signaling pathway | 1.46E-05 | 91 | 33 |
Thyroid hormone signaling pathway | 2.14E-05 | 76 | 33 |
Morphine addiction | 2.41E-05 | 58 | 32 |
Ras signaling pathway | 2.82E-05 | 137 | 38 |
mTOR signaling pathway | 4.85E-05 | 46 | 29 |
Renal cell carcinoma | 4.93E-05 | 49 | 29 |
ErbB signaling pathway | 5.78E-05 | 62 | 33 |
Oxytocin signaling pathway | 6.22E-05 | 100 | 31 |
