Figure 2 | Scientific Reports

Figure 2

From: SPARC expression is associated with hepatic injury in rodents and humans with non-alcoholic fatty liver disease

Figure 2

Pro-fibrogenic gene expression is increased in patients with NAFLD and high SPARC expression. NAFLD patients were grouped by hepatic SPARC mRNA expression. Patients with high SPARC expression had significantly higher collagen 1 alpha (A) and TGF-beta (B) mRNA expression in the liver. Data are mean ± sem, *p < 0.05. Comparison between groups was performed with Mann-Whitney U Test. mRNA expressions of both pro-fibronic genes were significantly correlated to SPARC expression (C,D). Spearman rank Test.

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