Table 1 Demographic and clinical data of obese patients separated by hepatic SPARC mRNA expression.

From: SPARC expression is associated with hepatic injury in rodents and humans with non-alcoholic fatty liver disease

 

SPARC low (n = 46)

SPARC high (n = 16)

Age at surgery (y)

50.7 ± 1.5

47.6 ± 2.3

Sex (m/f)

10/36

2/14

BMI (kg/m²)

51.0 ± 1.2

51.5 ± 1.7

Fasting glucose (mg/dl)

99.9 ± 4.5

115.0 ± 13.5

HbA1c (%)

5.7 ± 0.1

6.0 ± 0.2

Leukocytes (/nl)

14. ± 6.1

8.4 ± 0.5

Thrombocytes (/nl)

266.5 ± 12.5

300.2 ± 15.9

Erythrocytes (106/ml)

5.5 ± 0.8

4.8 ± 0.1

Bilirubin (mg/dl)

0.55 ± 0.05

0.50 ± 0.06

LDH (IU/l)

230.5 ± 8.3

213.3 ± 14.5

Creatinine (mg/dl)

0.98 ± 0.13

0.76 ± 0.05

Total cholesterol

197.6 ± 6.1

196.4 ± 6.2

LDL (mg/dl)

135.1 ± 4.8

127. ± 5.0

HDL(mg/dl)

44.8 ± 1.6

46.5 ± 2.5

Adipocyte cell diameter (µm)1

125 (75–150)

125 (100–150)

Adiponectin (ng/ml)

3.6 ± 0.4

4.1 ± 0.5

Steatosis1

1 (0–3)

1 (0–3)

Inflammation1

1 (0–3)

1 (1–3)

Ballooning1

1 (0–2)

1 (0–2)

NAFLD activity score1

3 (1–6)

3 (1–6)

  1. Data is given as mean ± standard error of mean. 1Data for these parameter is given as mean (range).