Figure 2 | Scientific Reports

Figure 2

From: Angiogenesis and evading immune destruction are the main related transcriptomic characteristics to the invasive process of oral tongue cancer

Figure 2

Contributions of each hallmark of cancer to invasion and metastasis, based on the KEGG pathways from protein coding genes. The intersections show the number of KEGG pathways (upper left panels) or genes (upper right panels). (A) All 292 KEGG pathways of the human genome (upper left panel) or genes related to 35238 human cDNAs annotated in Ensemble (upper right panel) and the distribution of the differentially expressed genes in all-3 comparisons of transformed cell lines (bottom panels, ZsG vs. LN1 left, LN1 vs. LN2 middle and LN2 vs. LN3 right), for p-values; (B) all 292 KEGG pathways of the human genome (upper left panel) or related to 3717 differentially expressed genes after FDR correction found in this study (upper right panel) and the distribution of the differentially expressed genes in all 3 comparisons of transformed cell lines (bottom panels, ZsG vs. LN1 left, LN1 vs. LN2 middle and LN2 vs. LN3 right) for q-values. In upper left panels were highlighted (in red) the changes of the number of KEGG pathways found in the transformed cell lines comparisons.

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