Figure 3
From: House dust mite induced allergic airway disease is attenuated in CD11ccreIL-4Rα−/l°x mice
Allergic airway disease in CD11ccreIL-4Rα−/lox mice in the house dust mite model (day 14). (A) Airway resistance and elastance after methacholine challenge in HDM-sensitized and challenged mice. (B) Eosinophils and neutrophils in the airways and lungs of challenged mice. (C) Mucus hypersecretion in the airways of challenged mice (100× magnification). (D) Goblet cell hyperplasia. HMI = histology mucous index. All graphs are representative of 2–3 experiments, with n = 5–6 per experiment. Significant differences are shown between IL-4Rα−/lox PBS and the other groups unless otherwise indicated by brackets. *P < 0.05; **P < 0.01; ***P < 0.001.
