Figure 4
From: House dust mite induced allergic airway disease is attenuated in CD11ccreIL-4Rα−/l°x mice
Reduced Th2 cytokine production in CD11ccreIL-4Rα−/lox mice sensitized and challenged with HDM (day 14). (A) Cytokine production by lung CD4+ T cells after stimulation with PMA/ionomycin/monensin. (B) Cytokine production by mediastinal lymph node cells after restimulation with HDM extract, measured by ELISA. (C) HDM-specific antibodies measured in serum by ELISA. Graphs are representative of two experiments. Significant differences are shown between IL-4Rα−/lox PBS and the other groups unless otherwise indicated by brackets. *P < 0.05; **P < 0.01; ***P < 0.001.
