Figure 3

Analyses of secreted proteins. (A,B) Comparative analyses of secreted genes from eight fungal strains. All genes and secretomes of each strain are represented by two bars. These genes are annotated in “cellular processes and signaling functional” (A) and “metabolism” (B) categories of the euKaryotic Clusters of Orthologous Groups (KOG) database. Eighteen clusters in KOG annotations are shown: [D], cell cycle control, cell division, chromosome partitioning; [Y], nuclear structure; [V], defense mechanisms; [T], signal transduction mechanisms; [M], cell wall/membrane/envelope biogenesis; [N], cell motility; [Z], cytoskeleton; [W], extracellular structures; [U], intracellular trafficking, secretion, and vesicular transport; [O], posttranslational modification, protein turnover, chaperones; [C], energy production and conversion; [G], carbohydrate transport and metabolism; [E], amino acid transport and metabolism; [F], nucleotide transport and metabolism; [H], coenzyme transport and metabolism; [I], lipid transport and metabolism; [P], inorganic ion transport and metabolism; [Q], secondary metabolites biosynthesis, transport and catabolism. P-values from the binomial tests for comparison of the proportion of annotated secreted proteins/annotated proteins and the proportion of all secreted proteins/all proteins in each KOG cluster are shown. (C) List of genes belonging to protease S10, S08A, and CAZymes GH18 families. (D–F) Phylogenies of genes in S10, S08A, and GH18 families, respectively. Three reported pathogenic factors are marked in bold and secreted proteins are identified by red circles. The bootstrap values of larger than or equal to 60 are shown.