Figure 4
The monomeric structures of IlvD/EDD enzymes: (a) CcXyDHT, (b) RlArDHT, and (c) So6PGDHT. The N-terminal domain is in red, the C-terminal domain in blue, and the connecting region is shown in green. The undefined regions in the structure of So6PGDHT are shown as dashed lines. The arrows indicate the major differences between the structures: 1) the N-terminal region, 2) the flipped helix-loop-helix structure, and 3) the β-hairpin insertion of So6PGDHT in the connecting region. (d) The location of sequence motifs 1 and 2 in the CcXyDHT monomer. The conserved residues in both motifs are in purple, and other residues are in grey.
