Table 1 Adams’s modularity test for the total sample and subsamples, modularity hypotheses and shape components. Columns presents covariance ratio (CR) and p-value. Bold and italic indicate the lowest CR value for asymmetric and symmetric component of the shape variation, respectively.

Source	Module	Component	CR	P-value
Total	Functional	Asymmetric	0.4841	0.001
	Functional	Symmetric	0.6148	0.001
	Facial third	Asymmetric	0.5030	0.001
	Facial third	Symmetric	0.8151	0.005
	Middle line	Asymmetric	0.5320	0.001
	Middle line	Symmetric	0.6559	0.001
	Neuro-face	Asymmetric	0.7145	0.003
	Neuro-face	Symmetric	0.7531	0.001
American	Functional	Asymmetric	0.5534	0.001
	Functional	Symmetric	0.6498	0.001
	Facial third	Asymmetric	0.5778	0.001
	Facial third	Symmetric	0.8542	0.006
	Middle line	Asymmetric	0.6052	0.001
	Middle line	Symmetric	0.6901	0.001
	Neuro-face	Asymmetric	0.8006	0.004
	Neuro-face	Symmetric	0.7651	0.001
European	Functional	Asymmetric	0.4997	0.001
	Functional	Symmetric	0.6110	0.001
	Facial third	Asymmetric	0.5264	0.001
	Facial third	Symmetric	0.8155	0.001
	Middle line	Asymmetric	0.5265	0.001
	Middle line	Symmetric	0.6572	0.001
	Neuro-face	Asymmetric	0.6890	0.002
	Neuro-face	Symmetric	0.7557	0.001
Admixed (Heterozygous)	Functional	Asymmetric	0.4903	0.001
	Functional	Symmetric	0.6238	0.001
	Facial third	Asymmetric	0.5039	0.001
	Facial third	Symmetric	0.8388	0.005
	Middle line	Asymmetric	0.5411	0.001
	Middle line	Symmetric	0.6670	0.001
	Neuro-face	Asymmetric	0.7292	0.003
	Neuro-face	Symmetric	0.7532	0.001
Homozygous	Functional	Asymmetric	0.5084	0.001
	Functional	Symmetric	0.6152	0.001
	Facial third	Asymmetric	0.5316	0.001
	Facial third	Symmetric	0.8432	0.006
	Middle line	Asymmetric	0.5440	0.001
	Middle line	Symmetric	0.6561	0.001
	Neuro-face	Asymmetric	0.7286	0.003
	Neuro-face	Symmetric	0.7692	0.001

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