Figure 1

PD-L1 fusion protein treatment significantly reduces pigment degradation in adult Pmel-1 mice. Pmel-1 mice with pigment loss conditions (21 weeks) were treated with mouse PD-L1 fusion protein or IgG control for 6 weeks. Photographs were taken 1 week after the last treatment. (A) Pigment loss of representative mice after treatment. (B) Quantification of all mice 3 weeks after the last treatment (Control group n = 9 cases, PD-L1 protein treated group n = 8 cases, *p < 0.05).