Figure 5 | Scientific Reports

Figure 5

From: Metabolomics profiling reveals differential adaptation of major energy metabolism pathways associated with autophagy upon oxygen and glucose reduction

Figure 5The alternative text for this image may have been generated using AI.

Mitochondrial content and degradation activity analyses (mitophagy) by confocal microscopy. (a) IMR90 cells stained with the mitochondrial marker MitoTracker red (MTr) and the mitophagy marker BNIP3L/Nix upon control, OR, GR and OGR. (b) Quantification of the MTr, BNIP3L/Nix as well as the BNIP3L/Nix to MTr ratio by measuring the total fluorescence. *p ≤ 0.05, **p ≤ 0.01. P-values were determined by one-way ANOVA with Dunnet’s multiple comparison’s test. Data represent mean ± s.e.m.

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