Figure 1
From: Night eating model shows time-specific depression-like behavior in the forced swimming test
Effect of duration of RF with HFD at ZT 5 on locomotor activity, body weight, and caloric intake (Experiment 1). (A) Feeding schedules of the control and NES model groups. Mice in the control group were fed with ND throughout the day. Mice in the NES model groups were fed with ND throughout the day and restricted feeding with HFD at ZT 5. (B) Relative locomotor activity rhythm at each time point of RF with HFD at ZT 5 (60, 30, 15, 5, and 1 min). Red triangles represent the start of RF. Open and closed bars indicate light and dark periods, respectively. (C) Sum of relative locomotor activity during ZT 5 and 9. (D) Increase in body weight. (E–G) Change in average caloric intake of total (E), ND (F), and HFD (G) at each RF duration. Data are presented as the mean ± standard error of the mean (SEM; control group, n = 6; NES model group, n = 8). *p < 0.05, **p < 0.01, ***p < 0.001 vs. the control group (Student’s t-test); #p < 0.05, ##p < 0.01, ###p < 0.001 vs. the control group (Mann-Whitney test).
