Figure 4 | Scientific Reports

Figure 4

From: Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa

Figure 4

(A) Combination effects of G1 and AiiA on PAO1-pqsA-gfp reporter strain. (B) Dose-response effects of G1 (50 µM) added with AiiA (32 µg/ml and 16 µg/ml) on pqsA-gfp. (C) IC50 values of the single and combination treatments on pqsA-gfp, G1 (3.08 ± 0.72 µM), AiiA (15.58 ± 0.17 µg/ml), G + A 32 µg/ml (0.63 ± 0.06 µM). Calculation was performed using GraphPad Prism 6 software, taken at the time point between 4–6 hours where the inhibition started to occur. Experiments were done in triplicate manner, only representative data are shown.

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