Table 2 Multiple cox regression analyses for bladder cancer development.

From: Estimating the impact of body mass index on bladder cancer risk: Stratification by smoking status

  

H.R (95% confidence interval)

Event

Person year

Incidence*

Model 1

Model 2

Age, years

 30–39

479

36,724,384.94

1.30

Ref.

Ref.

 40–64

9,493

72,038,460.09

13.18

10.11 (9.22, 11.08)

10.65 (9.71, 11.69)

 ≥65

11,932

17,555,627.37

67.97

52.03 (47.49, 57.01)

52.29 (47.58, 57.47)

Sex

 Male

17,979

64,487,512.03

27.88

Ref.

Ref.

 Female

3,925

61,830,960.37

6.35

0.23 (0.22, 0.24)

0.20 (0.19, 0.21)

Smoking status

 Non

9,077

78,119,887.32

11.62

Ref.

Ref.

 Ex

5,843

17,281,895.63

33.81

2.90 (2.81, 3.00)

1.32 (1.27, 1.37)

 Current

6,984

30,916,689.45

22.59

1.95 (1.89, 2.01)

1.52 (1.46, 1.57)

BMI, kg/m2

 <18.5

697

4,968,089.15

14.03

0.95 (0.88, 1.02)

0.92 (0.85, 1.00)

 18.5–22.9

7,482

50,015,687.14

14.96

Ref.

Ref.

 23.0–24.9

5,964

30,796,378.59

19.37

1.08 (1.05, 1.12)

1.09 (1.06, 1.13)

 25.0–29.9

7,145

35,933,349.62

19.88

1.13 (1.10, 1.17)

1.15 (1.11, 1.19)

 ≥30

616

4,604,967.91

13.38

1.16 (1.07, 1.26)

1.17 (1.05, 1.28)

Alcohol consumption

 Never drinkers

11,796

66,884,498.9

17.64

Ref.

Ref.

 Up to 30 g/day

8,059

49,695,192.9

16.22

0.92 (0.89, 0.95)

0.82 (0.79, 0.85)

 More than 30 g/day

1,800

8,250,025.06

21.82

1.24 (1.18, 1.30)

0.79 (0.75, 0.83)

Regularly Exercise

 No

11,479

62,586,593.14

18.34

Ref.

Ref.

 Yes

10,283

62,800,931.27

16.37

0.89 (0.87, 0.92)

0.959 (0.933, 0.986)

Hypertension

 No

10,565

93,064,967.88

11.35

Ref.

Ref.

 Yes

11,339

33,253,504.52

34.10

3.00 (2.92, 3.08)

1.29 (1.25, 1.33)

Dyslipidemia

 No

15,700

102,023,111.5

15.39

Ref.

Ref.

 Yes

6,204

24,295,360.9

25.54

1.66 (1.61, 1.71)

1.11 (1.08, 1.15)

Diabetes

 No

17,298

114,768,614.4

15.07

Ref.

Ref.

 Yes

4,606

11,549,857.98

39.88

2.65 (2.57, 2.74)

1.20 (1.16, 1.25)

  1. *All rates are expressed as number per 100,000 person-years.
  2. Univariate model.
  3. Full model of multiple cox regression.