Figure 7
Expression of GGA2 in human hepatocellular carcinoma (HCC) and colorectal carcinomas (CRC). (a) Western blot analysis of GGA2 and EGFR expressions in non-tumor (Non T; 4 cases) and tumor regions of HCCs (10 cases). Asterisks indicate bands for EGFR. Histological grade is shown for each case (see Supplementary Table S1 for more detail). Uncropped blots are presented in Supplementary Fig. 7. (b) Ratios of GGA2 to GAPDH were calculated and normalized to that of case #1. Statistical analysis was performed using Mann-Whitney U-test; *P < 0.05. (c) Paraffin sections of tumors and adjacent non-tumor regions (Non T) from three cases of HCC and CRC were immunostained using anti-GGA2 antibody. Histological grade is shown for each case. Boxed regions are magnified and shown in insets; Bars, 20 μm.
