Figure 1 | Scientific Reports

Figure 1

From: Mechanical phenotyping of K562 cells by the Micropipette Aspiration Technique allows identifying mechanical changes induced by drugs

Figure 1The alternative text for this image may have been generated using AI.

From (a) to (d): sequence of images (DIC contrast; scale bar =10 μm) of a K562 cell showing the increase of the cell-protrusion length inside the micropipette  after a pressure step of 30 Pa is applied by the micropipette aspiration set-up. The time associated to each image is reported. The dashed black lines have been introduced to mark the position of the cell protrusion in the different snapshots; (e) plot showing the cell protrusion variation with time for several cells. The protrusion length variation is normalized to the micropipette radius. The red line represents the averaged behavior. Inset: time variation of the measured pressure difference in the micropipette aspiration set-up. (f) plot of the average curve reported in e; (g) Log-Log representation of the average behavior for the control cells (the same as in f) to highlight the power-law fit to the data (continuous red line).

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