Table 1 Agonist sensitivity (pEC50) and % maximum response (Rmax) of endothelium-dependent and -independent relaxations to acetylcholine (ACh) and sodium nitroprusside (SNP) in aortic rings isolated from all treatment groups.

From: 3′,4′-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice

Group

ACh

SNP

pEC50 (log M)

Rmax (%)

pEC50 (log M)

Rmax (%)

Control

6.77 ± 0.08

91 ± 1

9.66 ± 1.91

96 ± 1

DiOHF

6.63 ± 0.09

92 ± 2

9.88 ± 3.06

97 ± 1

Tunica

6.83 ± 0.12

59 ± 5###

9.55 ± 2.77

96 ± 1

Tunica + DiOHF

6.72 ± 0.05

84 ± 2***

9.04 ± 1.08

96 ± 1

Tunica + TUDCA

6.72 ± 0.05

88 ± 4***

9.23 ± 1.69

95 ± 2

  1. Data are expressed as mean ± SEM (n = 6–8).
  2. ###P < 0.001 compared vs control.
  3. ***P < 0.001 compared vs tunica.
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