Table 4 Gene Ontology Top 20 5xFAD 10 weeks upregulated proteins compared to 5xFAD 6 weeks.

From: Innate immune alterations are elicited in microglial cells before plaque deposition in the Alzheimer’s disease mouse model 5xFAD

Proteins

Name

Location

Ppp1r21

Protein phosphatase 1 regulatory subunit 21

2p16.3

Gtf3c5

General transcription factor IIIC subunit 5

9q34.13

Smchd1

Structural maintenance of chromosomes flexible hinge domain containing 1

18p11.32

Tdrd7

tudor domain containing 7

9q22.33

Sugp1

SURP and G-patch domain containing 1

19p13

Sh3glb1

SH3 domain containing GRB2 like, endophilin B1

1p22.3

Cherp

Calcium homeostasis endoplasmic reticulum protein

19p13.11

Fam129a

Family with sequence similarity 129 member A

1q25.3

Cenpv

Centromere protein V

17p11.2

Coasy

Coenzyme A synthase

17q21.2

Ndrg3

NDRG family member 3

20q11.23

Plek

pleckstrin

2p14

Prpf6

pre-mRNA processing factor 6

20q13.33

Fmnl3

formin like 3

12q13.12

Mad1l1

MAD1 mitotic arrest deficient like 1

7p22.3

Anxa7

annexin A7

10q22.2

Cmtr1

cap methyltransferase 1

6p21.2

Gvin1

GTPase, very large interferon inducible pseudogene 1

11p15.4

Parp2

Poly(ADP-ribose) polymerase 2

14q11.2

Gnl3

G protein nucleolar 3

3p21.1

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