Figure 8

Reduction of radio-opacity in the renal cortex of UUO kidneys in comparison to sham operated kidneys. Box plots of grey values of 6 cortical cubes per kidney are shown (A) The mean density value of all analyzed virtual cortical cubes which were generated from the CT datasets is significantly higher in sham treated kidneys (3575 ± 94.5 GV) than in UUO kidneys (3039 ± 105.5 GV). (B) The sham operated animals also show the highest values for the maximum radio-opacity (3916 ± 102.1 GV), reflecting a stronger uptake of PTA in the unaffected renal cortex than in the renal cortex of UUO treated mice (3302 ± 61.9 GV).