Figure 8

Importance of growth and remodeling kinetics. The relative rates k of growth (k = k_g) and remodeling (k = k_r) with respect to the environmental changes were altered to study their effects on the temporal stretch evolution. Three cases were investigated for early (a–c) and late-stage (d–f) development: (a,d) changing growth rate k_g and remodeling rate k_r simultaneously, (b,e) changing only the growth rate k_g while k_r = 0, and (c,f) changing only the remodeling rate k_r while k_g = 0. Growth and remodeling occurred with the same rate as the environmental changes if k = 0, initially slower if k < 0; and initially faster if k < 0. The three-dimensional circumferential stretch distributions are shown halfway the developmental steps at time point 0.5 for k_g = ±3 and/or k_r = ±3.