Figure 6 | Scientific Reports

Figure 6

From: Delayed onset of autoreactive antibody production and M2-skewed macrophages contribute to improved survival of TACI deficient MRL-Fas/Lpr mouse

Figure 6

Spontaneous GC, Tfh and Thef accumulations were not altered in TACI deficient MRL-Fas/Lpr mice. Percentages of CD19 + CD3-GL7 + PNA + GC B cells (A), CXCR4-CXCR5+ PD1+ PSGL1loCD62L-CD44+ Tfh cells (B), CXCR4+ CXCR5-PD1+ PSGL1loCD62L-CD44+ Thef cells (C) in spleens of 6 to 12 weeks old LPR-TACI+/+, LPR-TACI+/− and LPR-TACI−/− mice were quantified in flow cytometry. Mean percentage ± SD from 4 to 6 mice in each group were plotted. *p < 0.05 indicates statistical difference between LPR-TACI+/+ and LPR-TACI−/− mice.

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