Figure 1 | Scientific Reports

Figure 1

From: Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics

Figure 1

Differential gene network comparing HDMS nonwheezers versus nonatopic controls. Differentially expressed genes were identified with an edgeR analysis. Gene expression patterns in sputum were compared between HDMS nonwheezers and nonatopic controls. The wiring diagram of the underlying gene network was reconstructed employing prior knowledge from the literature (Ingenuity Knowledge Base). Genes highlighted in red denote upregulation, whilst green indicates downregulation in HDMS nonwheezers.

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