Figure 2 | Scientific Reports

Figure 2

From: Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics

Figure 2

Differential gene network comparing HDMS wheezers versus nonatopic controls. Differentially expressed genes were identified with an edgeR analysis. Gene expression patterns in sputum were compared between HDMS wheezers and nonatopic controls. The wiring diagram of the underlying gene network was reconstructed using prior knowledge from the literature (Ingenuity Knowledge Base). Genes highlighted in red denote upregulation, whilst molecules in green indicate downregulation in HDMS wheezers.

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