Table 2 The results of family-based association test between rs2248359 and T2DM.

From: Maternal transmission disequilibrium of rs2248359 in type 2 diabetes mellitus families and its association with vitamin D level in offspring

Model

Allele

afreq

Fam#

S-E(S)

Var(S)

Z

P

Additive

C

0.617

16

−5

6

−2.041

0.041227

T

0.383

16

5

6

2.041

0.041227*

Dominant

T

0.383

13

5

3.375

2.722

0.006496*

Recessive

C

0.617

13

−5

3.375

−2.722

0.006496

  1. Note: 232 pedigrees containing 280 T2DM patients were read in FBAT software. S-E(S) and Var (S) are the expected value and variance of the test statistic. Z: the test statistic; P: significance level. *The significant association between allele and T2DM (Z > 0 and P < 0.05).
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