Figure 3
From: The antidepressant fluoxetine acts on energy balance and leptin sensitivity via BDNF
FLX affects hypothalamic expression of BDNF and modifies WAT expression profile. mRNA values were determined by quantitative reverse transcription–PCR and standardized to TATA Binding Protein (TBP) in the hypothalamus (A) and in the EPI WAT (B) of H2O-CFD and FLX-CFD. Student’s t-test: (A) BDNF (t = 2.577 df = 14, *P = 0.022; n = 8); (B) CIDEA (t = 4.099 df = 15, ***P = 0.0009; n = 8–9); Prdm16 (t = 2.175 df = 14, *P = 0.047; n = 8); LPL (t = 2.151 df = 14, *P = 0.049; n = 8); FAS (t = 2.592 df = 14, *P = 0.021; n = 8). Data are presented as mean ± s.e.m.
