Figure 5
From: Modulation of oncogenic miRNA biogenesis using functionalized polyamines
(A) Phase contrast microscopic observations of living GC tumorspheres without treatment or after in the presence of compound PA-1 at 10 and 25 µM for 5 days, using an inverted-light microscope (Zeiss) equipped with a 10 × objective. Bars = 100 µm. (B) Numeration of GC10 tumorpheres per well in the presence of growing concentrations of PA-1 measured at day 5 of treatment. Bars represent the mean ± SD of tumorphere number compared to untreated cells (out of 6 experiments, with 10 wells per condition).
