Figure 7
From: Modulation of oncogenic miRNA biogenesis using functionalized polyamines
Docking of compound PA-1 with the pre-miR-372 hairpin loop performed using autodock 4 where the grid boxes were fixed on the entire RNA sequence. (A) First possible docking of compound 1 close to the G16 internal bulge and (B) second possible docking conformation of compound PA-1 at the junction between the stem and the terminal loop.
