Figure 2
Cross-correlation of spontaneous membrane potential (Vm) in the ACC neurons was increased continuously after CCI surgery, and this increase was reversed by Meflo. (a) Schematic diagram for in vivo dual patch clamp whole-cell recording from ACC neurons (b) Representative spontaneous Vm recorded in pairs of ACC neurons in vivo from different groups. Scale bars represent 20 mV and 500 ms. (c) Cross correlation of spontaneous Vm in pairs of ACC neurons from the sham, CCI and Meflo groups. A strong correlation was observed at zero time lag in the CCI group. Cross-correlation was increased in the CCI group compared with the sham group and decreased relative to the Meflo group. (d) Average correlation coefficients between spontaneous Vm in ACC neurons for the sham, CCI and Meflo groups (one-way ANOVA, *P < 0.05, CCI compared with the sham group; ***P < 0.001, compared with the Meflo group, n = 9). (e) Correlation coefficients in ACC neurons computed from the 1 min epoch differ little from coefficients computed from other 1 min recordings in the sham and CCI groups.
