Figure 4 | Scientific Reports

Figure 4

From: Membrane potential synchrony of neurons in anterior cingulate cortex plays a pivotal role in generation of neuropathic pain

Figure 4

Nerve injury induces activation of higher-frequency (gamma rhythms) and lower-frequency (theta and delta rhythms) membrane potential synchrony in ACC neurons, and Meflo reverses activation induced by CCI surgery. (a) Power spectra of higher-frequency (gamma rhythms) membrane potential synchrony of neurons in the anterior cingulate cortex. (b) Summary results of the power of higher-frequency (gamma rhythms) membrane potential synchrony in ACC neurons from the sham, CCI and Meflo groups (one-way ANOVA, *P < 0.05, n = 18 for each group). (c) Peak frequency from the sham, CCI and Meflo groups (n = 18 for each group). (d) Power spectra of lower-frequency (delta rhythms) membrane potential synchrony of neurons in the anterior cingulate cortex. (e) Summary results of the power of lower-frequency (delta rhythms) membrane potential synchrony in the ACC neurons from the sham, CCI and Meflo groups (one-way ANOVA, *P < 0.05, n = 18 for each group). (f) Peak frequency from the sham, CCI and Meflo groups (n = 18 for each group). (g) Power spectra of lower-frequency (theta rhythms) membrane potential synchrony of neurons in the anterior cingulate cortex. (h) Summary results of the power of lower-frequency (theta rhythms) membrane potential synchrony in ACC neurons from the sham, CCI and Meflo groups (one-way ANOVA, *P < 0.05, n = 18 for each group). (i) Peak frequency from the sham, CCI and Meflo groups (n = 18 for each group).

Back to article page