Table 1 Overview of different WMH shape features per lesion.

From: White matter hyperintensity shape and location feature analysis on brain MRI; proof of principle study in patients with diabetes

 

Mean

Minimum

Maximum

Skewness

Kolmogorov-Smirnov

Area based

 Surface area†

0.01

0.00

1.09

13.82

p < 0.001

Dimension/volume based

 Eccentricity

2.52

1.00

8.97

1.57

p < 0.001

 Compactness1

0.0039

0.0001

0.0073

−0.10

p < 0.001

 Compactness2

0.52

0.03

1.00

0.25

p < 0.001

 Compactness3

0.20

0.00

1.00

1.14

p < 0.001

Complex features

 Fractal dimensions

1.37

0.00

2.62

−0.51

p < 0.001

 Shape index

−0.64

−0.73

−0.45

0.86

p < 0.001

 Curvedness

2.30

0.63

7.71

2.20

p < 0.001

  1. Mean, minimum, maximum, skewness and output of the Kolmogorov-Smirnov test are shown for different WMH shape features. These values were calculated per lesion on the combined patient and control group.
  2. †Corrected for intracranial volume.
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