Table 2 Characteristics of the subject groups.

From: White matter hyperintensity shape and location feature analysis on brain MRI; proof of principle study in patients with diabetes

 

Patients with T2DM (n = 60)

Control participants (n = 54)

p-values

Characteristics

 Men (%)

35 (58)

32 (59)

0.920

 Age (years)

71.0 ± 4.3

71.2 ± 4.7

0.794

 Mean arterial pressure (mmHg)†

103 ± 10

102 ± 11

0.613

 HbA1c (%)‡

6.7 (5.9–7.8)

5.6 (5.3–6.2)

<0.001

 Diabetes duration (years)

10.6 ± 8.7

—

—

MRI

 Lacunar infarcts (%)

20 (33)

17 (31)

0.833

 Large vessel infarcts (%)

4 (7)

1 (2)

0.203

 Gray matter volume (%ICV)

38.0 ± 2.3

39.1 ± 2.1

0.009

 White matter volume (%ICV)

29.8 ± 2.4

30.2 ± 3.0

0.447

  1. Data are n (percentage), mean ± SD or median (10th–90th percentile).
  2. †Systolic and diastolic blood pressure were measured on three different time points. The mean arterial pressure was calculated from the averaged systolic and diastolic blood pressure.
  3. ‡Determined with standardized laboratory testing.
  4. T2DM: type 2 diabetes mellitus. %ICV: percentage of intracranial volume.
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