Table 4 WMH shape and location features per lesion for punctuate deep WMH.

From: White matter hyperintensity shape and location feature analysis on brain MRI; proof of principle study in patients with diabetes

 

Punctuate deep WMH in patients with T2DM (n = 866)

Punctuate deep WMH in control participants (n = 881)

p-values

Location (number)

 Frontal

594 (68%)

561 (64%)

0.550

 Temporal

46 (5%)

74 (8%)

0.390

 Parietal

213 (25%)

234 (27%)

0.747

 Occipital

13 (2%)

12 (1%)

0.561

Shape (eccentricity)

 Frontal

2.06 (1.40–3.06)

1.81 (1.30–2.64)

<0.001

 Temporal

1.86 (1.35–2.96)

1.66 (1.27–2.50)

0.084

 Parietal

1.99 (1.38–2.99)

1.81 (1.35–2.75)

0.001

 Occipital

2.00 (1.32–2.84)

1.78 (1.33–2.79)

0.769

  1. Location (n (percentage)) and shape (median (10th–90th percentile)) are shown per lesion for punctuate deep WMH. For location, χ2 tests were performed on the percentages. For shape, Mann Whitney U tests were performed on the eccentricity values. Because of the limited sample size the 17 WMH located in the basal ganglia region and cerebellum are not presented in this table.
  2. T2DM: type 2 diabetes mellitus. WMH: white matter hyperintensities.