Table 4 Phenotyping results of George Bähr.

From: Inferring genetic origins and phenotypic traits of George Bähr, the architect of the Dresden Frauenkirche

SNP

Gene

LCT

SLC45A2

SLC45A5

EDAR

HERC2

rs4988235

rs16891982

rs1426654

rs3827760

rs12913832

Ancestral

G

C

G

A

A

Derived

A

G

A

G

G

Coverage

\(39\times \)

\(114\times \)

8 \(\times \)

\(43\times \)

46 \(\times \)

Derived allele frequency

50%

100%

100%

0%

57%

  1. To ensure consistency, the analysis was limited to high quality bases (q > 30) and duplicates were removed after merging of both sequencing libraries. The SNP RS4988235 in LCT is responsible for lactase persistence in Europe37,38. Both SNPs at SLC24A5 and SLC45A2 are considered to be responsible for light skin pigmentation39, whereas the SNP in HERC2 is the primary determinant of light eye color in present-day Europeans40,41. The SNP in the gene EDAR affects tooth morphology and hair thickness42,43, and was not found to be derived in the investigated sample. All these results were obtained on the 390K SNP capture dataset.
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