Table 2 Major functional categories overrepresented in lists of genes with the highest in-degree.

From: Comprehensive network of miRNA-induced intergenic interactions and a biological role of its core in cancer

Term

F-network adj. p-val

IS-network adj. p-val

Cell cycle

1.09 × 10−5

1.16 × 10−5

p53 signalling pathway

3.11 × 10−5

3.62 × 10−5

Pathways in cancer

2.15 × 10−5

4.24 × 10−4

Focal adhesion

6.54 × 10−4

5.25 × 10−4

Apoptosis

1.17 × 10−3

1.21 × 10−3

Posttranscriptional regulation of gene expression

3.32 × 10−5

1.63 × 10−3

Transcription regulation

4.12 × 10−3

1.19 × 10−2

  1. F-network adj. p-val – Benjamini-corrected p-value for the F-network list reported by DAVID; IS-network adj. p-val – Benjamini-corrected p-value for the IS-network list reported by DAVID.
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