Table 2 Objective and subjective image quality between DE CTPA VMS and the standard CTPA datasets.

From: CT pulmonary angiography in patients with acute or chronic renal insufficiency: Evaluation of a low dose contrast material protocol

 

Low CM DECT

Standard CM DECT

Standard CTPA

p-value

40 keV[A]

50 keV[B]

40 keV[C]

50 keV[D]

[E]

Main pulmonary arteries

A vs C

B vs D

B vs E

D vs E

 Attenuation

649.2 ± 59.7

437.4 ± 39.5

850.2 ± 242.5

575.3 ± 161.3

375.7 ± 120.3

<0.0001

<0.0001

0.0022

<0.0001

 Signal-to-noise-ratio

16.1 ± 2.8

16.8 ± 2.8

21.5 ± 9.1

22.1 ± 9.3

14.0 ± 3.7

<0.0001

<0.0001

0.0002

<0.0001

 Contrast-to-noise-ratio

14.4 ± 2.4

14.5 ± 2.4

20.7 ± 9.1

20.8 ± 9.1

12.7 ± 3.5

<0.0001

<0.0001

0.0073

<0.0001

 Subjective image quality

4[4–5]

5[4–5]

4[4–5]

5[4–5]

5[4–5]

0.8762

0.7335

0.6581

0.6632

 Subjective image noise

4[3–4]

4[3–5]

4[3–4]

4[4–5]

4[3–5]

0.8571

0.7684

0.8039

0.1344

Peripheral pulmonary arteries

A vs C

B vs D

A vs E

C vs E

 Attenuation

545.4 ± 74.2

358.5 ± 48.0

857.4 ± 246.0

580.1 ± 163.5

358.8 ± 110.4

<0.0001

<0.0001

<0.0001

<0.0001

 Signal-to-noise-ratio

13.8 ± 6.2

14.0 ± 5.9

14.6 ± 6.3

15.1 ± 6.4

9.7 ± 4.5

0.4045

0.3017

<0.0001

<0.0001

 Contrast-to-noise-ratio

12.1 ± 5.5

11.7 ± 5.1

14.1 ± 6.3

14.1 ± 6.3

8.8 ± 4.2

0.1466

0.0538

0.0064

<0.0001

 Subjective image quality

5[4–5]

5[4–5]

5[4–5]

5[4–5]

5[4–5]

0.7976

0.8112

0.3475

0.7214

 Subjective image noise

4[3–4]

4[3–5]

4[3–4]

4[3–5]

4[3–4]

0.9117

0.8549

0.1224

0.1463

  1. Note VMS = virtual monoenergetic spectral; CTPA = CT pulmonary angiography; keV = kiloelectron Volt; values in brackets represent the 25–75% interquartile.