Figure 6 | Scientific Reports

Figure 6

From: miR-429 suppresses tumor migration and invasion by targeting CRKL in hepatocellular carcinoma via inhibiting Raf/MEK/ERK pathway and epithelial-mesenchymal transition

Figure 6

The effect of CRKL knockdown on cell adhesion ability and cytoskeleton F-actin in HepG2. (A) CRKL knockdown inhibited the in situ LN adhesion capacity of HepG2 cells (**** refers to P < 0.0001). (B) CRKL knockdown inhibited the extracellular matrix adhesion ability of HepG2 cells to FN by MTT assay (****P < 0.0001). (C) CRKL knockdown decreased cytoskeleton F-actin protein expression and filament arrangement of HepG2 cells by FITC-phalloidin assay.

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