Figure 1
From: Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice
The upper schema illustrates a cell culture of hiPSCs in vitro and cell transplantation into the otocysts in vivo. The hiPSCs were cultured for 25 days and differentiated into progenitors of OSCs. We utilized these progenitors of OSCs as donor cells. To confirm the developmental potency of these cells, they were cultured for another 2 weeks. The lower schema illustrates the otocystic injection procedure, and the schedule of the in vivo experiment. IHC: immunohistochemical analysis; ABR: auditory brain stem response.
