Table 2 Clinical symptoms and course of healthy control, unipolar depression and bipolar II depression.

Montgomery-Åsberg Depression Rating Scale, mean (s.d.)

0.15 (0.43)

23.20 (5.41)^a

21.55 (9.67)^a

164.45

<0.001**

Young Mania Rating Scale, mean (s.d.)

0.00 (0.00)

1.83 (2.82)^a,b

4.30 (5.17)^a,b

13.22

<0.001**

Hamilton Anxiety Rating Scale, mean (s.d.)

1.83 (2.82)

21.11 (8.80)^a

19.50 (9.71)^a

72.20

<0.001**

Age at onset of depression, mean (s.d.)

22.34 (4.98)^b

18.30 (5.55)^b

7.71

0.01*

Years since depression onset, mean (s.d.)

2.60 (2.78)^b

4.90 (3.86)^b

6.53

0.01*

Total number of major depressive episodes, mean (s.d.)

1.43 (0.70)^b

2.60 (1.54)^b

64.52

<0.001**

Total number of hypomanic episodes, mean (s.d.)

71.65 (106.5)

Short-form 36 - physical component summary, mean (s.d.)

55.62 (4.06)

49.15 (7.52)^a**

49.81 (7.01)^a**

10.66

<0.001**

Short-form 36 - mental component summary, mean (s.d.)

54.04 (4.18)

27.90 (10.01)^a**

26.96 (11.04)^a**

103.44

<0.001**