Table 3 Chondroitin sulphate and glucosamine association to risk of CRC.

From: Possible role of chondroitin sulphate and glucosamine for primary prevention of colorectal cancer. Results from the MCC-Spain study

 

OR

95% CI

P-value

Crude effecta

0.47

0.28–0.79

0.0023

Adjusted for ASA use

0.47

0.28–0.79

0.0045

Adjusted for non-ASA NSAIDs use

0.72

0.43–1.23

0.23

Adjusted for NSAIDs use

0.62

0.37–1.05

0.077

Adjusted for multivariateb without NSAIDs use

0.52

0.31–0.88

0.017

Adjusted for multivariateb

0.82

0.47–1.40

0.37

  1. aAdjusted by the study design variables (age, gender, region and education).
  2. bAdjusted by the study design variables plus alcohol consumption, BMI, physical activity, vegetables and red meat intake, family history and NSAIDs use (see Table 3).
  3. ASA: acetylsalicylic acid; NSAID: Nonsteroidal anti-inflammatory drugs (includes ASA except when indicated).