Figure 4
From: Formation of Multi-Component Extracellular Matrix Protein Fibers
3D confocal images and SEM images with schematic animations. 3D-reconstructed z-stack images (upper panels) and molecular-level animations (middle panels) of (a,b) locally patched composite ECM fibers, (c,d) hetero-stacked composite ECM fibers, and (e, f) sandwiched composite ECM fibers of COL (green) and FN (red). The scales of (a,c and e) are 50 µm. (g) The graph shows the thickness of single-component and multi-component ECM protein fibers (n = 3; the error bars indicate the standard error of the mean). (h–i) SEM images of (h) LAM on FN and (i) COL on FN. White arrows indicate stacked single fibers or composite fibers. The scales of (h) and (i) are 1 µm.
