Figure 6 | Scientific Reports

Figure 6

From: Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK pathways

Figure 6

Schematic diagram presenting pathways where SMG-induced inhibition of focal adhesions suppresses FAK/RhoA activation and consequently the mTORC1 signaling and cell glycolysis while activating the AMPK pathway and inducing mitochondria biogenesis, leading to the inhibition of tumor cell proliferation and metastasis.

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